Electrophoretic purification of a water-soluble guinea pig transplantation antigen.
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چکیده
منابع مشابه
Electrophoretic purification of a water-soluble guinea pig transplantation antigen.
The isolation of tissue transplantation antigens has been energetically pursued since Billingham et al.' found that cell extracts could induce homograft immunity. A major problem in this endeavor has been the solubilization of the antigens which probably reside on cellular membranes. Studies employing tissue homogenization' and pressure decompression' to disrupt cells have yielded insoluble ant...
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Antibodies can be considered to be molecules with two distinct sets of properties: the capacity to react specifically with antigen, and the capacity to mediate a variety of biological reactions. Some of these are: anaphylaxis, which in the guinea pig may depend upon the ability of these molecules to react with unidentified tissue receptors (1) or cell lysis (2, 3) and opsonization (4, 5) which ...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1967
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.58.4.1430